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β4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium
VM Weaver et al.
CANCER CELL (2002)
Dissemination and growth of cancer cells in metastatic sites
AF Chambers et al.
NATURE REVIEWS CANCER (2002)
Metastasis is driven by sequential elevation of H-ras and Smad2 levels
M Oft et al.
NATURE CELL BIOLOGY (2002)
Interaction between the transforming growth factor-β type II receptor/Smad pathway and β-catenin during transforming growth factor-β1-mediated adherens junction disassembly
YC Tian et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
The integrin αvβ8 mediates epithelial homeostasis through MT1-MMP-dependent activation of TGF-β1
DZ Mu et al.
JOURNAL OF CELL BIOLOGY (2002)
Integrin β1 signaling is necessary for transforming growth factor-β activation of p38MAPK and epithelial plasticity
NA Bhowmick et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
TGF-β signaling in tumor suppression and cancer progression
R Derynck et al.
NATURE GENETICS (2001)
Functional characterization of transforming growth factor β signaling in Smad2-and Smad3-deficient fibroblasts
E Piek et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The adaptor molecule Disabled-2 links the transforming growth factor β receptors to the Smad pathway
BA Hocevar et al.
EMBO JOURNAL (2001)
Ligand-dependent degradation of Smad3 by a ubiquitin ligase complex of ROC1 and associated proteins
M Fukuchi et al.
MOLECULAR BIOLOGY OF THE CELL (2001)
Smurf1 interacts with transforming growth factor-β type I receptor through Smad7 and induces receptor degradation
T Ebisawa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Malignant MCF10CA1 cell lines derived from premalignant human breast epithelial MCF10AT cells
SJ Santner et al.
BREAST CANCER RESEARCH AND TREATMENT (2001)
Transforming growth factor-beta 1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism
NA Bhowmick et al.
MOLECULAR BIOLOGY OF THE CELL (2001)
Hgs (Hrs), a FYVE domain protein, is involved in Smad signaling through cooperation with SARA
S Miura et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGFβ receptor for degradation
P Kavsak et al.
MOLECULAR CELL (2000)
Phosphatidylinositol 3-kinase function is required for transforming growth factor β-mediated epithelial to mesenchymal transition and cell migration
AV Bakin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-β signaling
X Lin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Inactivation of Smad-transforming growth factor β signaling by Ca2+-calmodulin-dependent protein kinase II
SJ Wicks et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Raf induces TGFβ production while blocking its apoptotic but not invasive responses:: a mechanism leading to increased malignancy in epithelial cells
K Lehmann et al.
GENES & DEVELOPMENT (2000)
Mechanisms of disease:: Role of transforming growth factor β in human disease.
GC Blobe et al.
NEW ENGLAND JOURNAL OF MEDICINE (2000)
Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis
RB Hazan et al.
JOURNAL OF CELL BIOLOGY (2000)
STRAP and Smad7 synergize in the inhibition of transforming growth factor β signaling
PK Datta et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
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