Journal
JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS
Volume 323, Issue 10, Pages 1417-1422Publisher
ELSEVIER
DOI: 10.1016/j.jmmm.2010.11.062
Keywords
Magnetic nanoparticle; Heat dissipation; Tumor therapy
Funding
- Grants-in-Aid for Scientific Research [22310064] Funding Source: KAKEN
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We have numerically simulated the dynamic response of single-domain nanomagnets to alternating magnetic fields and discuss nanometer-sized thermal seeds suitable for selectively targeted magnetic hyperthermia. When we assign priority to the easy delivery and biological safety of these fields, the maximum heating power is obtained by the irradiation of a weak field at a medium frequency (similar to 1 MHz) on almost spherical magnetite nanomagnets with a diameter of approximately 20 nm. On the other hand, the irradiation of the amplified field at a low frequency (similar to 100 kHz) is more effective if the neural stimulation is allowable. (C) 2010 Elsevier B.V. All rights reserved.
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