Journal
JOURNAL OF MAGNETIC RESONANCE IMAGING
Volume 39, Issue 2, Pages 360-368Publisher
WILEY
DOI: 10.1002/jmri.24183
Keywords
thoracic aorta; MRI; normal value; cardiovascular risk factors
Funding
- National Heart, Lung, and Blood Institute
- NIH [N01-HC-95159, N01-HC-95169]
Ask authors/readers for more resources
PurposeTo determine the normal size and wall thickness of the ascending thoracic aorta (AA) and its relationship with cardiovascular risk factors in a large population-based study. Materials and MethodsThe mean AA luminal diameter was measured in 3573 Multi-Ethnic Study of Atherosclerosis (MESA) participants (age: 45-84 years), using gradient echo phase contrast cine MRI. Multiple linear regression models were used to evaluate the associations between risk factors and AA diameter. The median and upper normal limit (95th percentile) was defined in a healthy subgroup as well as AA wall thickness. ResultsThe upper limits of body surface area indexed AA luminal diameter for age categories of 45-54, 55-64, 65-74, and 75-84 years are 21, 22, 22, and 28 mm/m(2) in women and 20, 21, 22, 23 mm/m(2) in men, respectively. The mean AA wall thickness was 2.8 mm. Age, gender, and body surface area were major determinants of AA luminal diameter (approximate to+1 mm/10 years; approximate to+1.9 mm in men than women; approximate to+1 mm/ 0.23 m(2); P<0.001). The AA diameter in hypertensive subjects was +0.9 mm larger than in normotensives (P<0.001). ConclusionAA diameter increases gradually with aging for both genders among all race/ethnicities. The normal value of AA diameter is provided. J. Magn. Reson. Imaging 2014;39:360-368. (c) 2013 Wiley Periodicals, Inc.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available