Related references
Note: Only part of the references are listed.Sirtuin 6 protects cardiomyocytes from hypertrophy in vitro via inhibition of NF-?B-dependent transcriptional activity
Shan-Shan Yu et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine
Hong Jiang et al.
NATURE (2013)
The Evolution and Refinement of Traditional Risk Factors for Cardiovascular Disease
Emil M. deGoma et al.
CARDIOLOGY IN REVIEW (2012)
Regulation of cholesterol homeostasis
Leigh Goedeke et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2012)
Hepatic Suppression of Foxo1 and Foxo3 Causes Hypoglycemia and Hyperlipidemia in Mice
Kebin Zhang et al.
ENDOCRINOLOGY (2012)
Nmnat2 protects cardiomyocytes from hypertrophy via activation of SIRT6
Yi Cai et al.
FEBS LETTERS (2012)
The NAD+-dependent Histone Deacetylase SIRT6 Promotes Cytokine Production and Migration in Pancreatic Cancer Cells by Regulating Ca2+ Responses
Inga Bauer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
NAD+-dependent Sirtuin 1 and 6 Proteins Coordinate a Switch from Glucose to Fatty Acid Oxidation during the Acute Inflammatory Response
Tie Fu Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Progression of Chronic Liver Inflammation and Fibrosis Driven by Activation of c-JUN Signaling in Sirt6 Mutant Mice
Cuiying Xiao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
The Deacetylase Sirt6 Activates the Acetyltransferase GCN5 and Suppresses Hepatic Gluconeogenesis
John E. Dominy et al.
MOLECULAR CELL (2012)
The sirtuin SIRT6 regulates lifespan in male mice
Yariv Kanfi et al.
NATURE (2012)
Liver cancer initiation is controlled by AP-1 through SIRT6-dependent inhibition of survivin
Lihua Min et al.
NATURE CELL BIOLOGY (2012)
The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun
Nagalingam R. Sundaresan et al.
NATURE MEDICINE (2012)
Over Expression of Wild Type or a Catalytically Dead Mutant of SIRTUIN 6 Does Not Influence NFκB Responses
Rachel Grimley et al.
PLOS ONE (2012)
Sirtuin 6 (SIRT6) rescues the decline of homologous recombination repair during replicative senescence
Zhiyong Mao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
SREBPs: metabolic integrators in physiology and metabolism
Tae-Il Jeon et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2012)
C. elegans SIRT6/7 Homolog SIR-2.4 Promotes DAF-16 Relocalization and Function during Stress
Wei-Chung Chiang et al.
PLOS GENETICS (2012)
Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGF-β-induced senescence of human bronchial epithelial cells
Shunsuke Minagawa et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2011)
A Conserved SREBP-1/Phosphatidylcholine Feedback Circuit Regulates Lipogenesis in Metazoans
Amy K. Walker et al.
CELL (2011)
SIRT6 overexpression induces massive apoptosis in cancer cells but not in normal cells
Michael Van Meter et al.
CELL CYCLE (2011)
Nuclear Receptors in Liver Disease
Martin Wagner et al.
HEPATOLOGY (2011)
Hepatic FoxOs Regulate Lipid Metabolism via Modulation of Expression of the Nicotinamide Phosphoribosyltransferase Gene
Rongya Tao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
SREBP-2: A link between insulin resistance, hepatic cholesterol, and inflammation in NASH
Derrick M. Van Rooyen et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2011)
Activation of Peroxisome Proliferator-Activated Receptor Gamma by Rosiglitazone Increases Sirt6 Expression and Ameliorates Hepatic Steatosis in Rats
Soo Jin Yang et al.
PLOS ONE (2011)
SIRT6 Promotes DNA Repair Under Stress by Activating PARP1
Zhiyong Mao et al.
SCIENCE (2011)
Dynamic Chromatin Localization of Sirt6 Shapes Stress- and Aging-Related Transcriptional Networks
Tiara L. A. Kawahara et al.
PLOS GENETICS (2011)
Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data
Mette Soerensen et al.
AGING CELL (2010)
SIRT6 protects against pathological damage caused by diet-induced obesity
Yariv Kanfi et al.
AGING CELL (2010)
Sterol metabolism and SREBP activation
Ryuichiro Sato
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2010)
The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α
Lei Zhong et al.
CELL (2010)
Hepatic-Specific Disruption of SIRT6 in Mice Results in Fatty Liver Formation Due to Enhanced Glycolysis and Triglyceride Synthesis
Hyun-Seok Kim et al.
CELL METABOLISM (2010)
Diabetes and Insulin in Regulation of Brain Cholesterol Metabolism
Ryo Suzuki et al.
CELL METABOLISM (2010)
Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP
Amy K. Walker et al.
GENES & DEVELOPMENT (2010)
Hepatic FoxO1 Ablation Exacerbates Lipid Abnormalities during Hyperglycemia
Rebecca A. Haeusler et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
SIRT1 Deacetylates and Inhibits SREBP-1C Activity in Regulation of Hepatic Lipid Metabolism
Bhaskar Ponugoti et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
SIRT6 Deficiency Results in Severe Hypoglycemia by Enhancing Both Basal and Insulin-stimulated Glucose Uptake in Mice
Cuiying Xiao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Effects of FoxO4 overexpression on cholesterol biosynthesis, triacylglycerol accumulation, and glucose uptake
Jun Zhu et al.
JOURNAL OF LIPID RESEARCH (2010)
Effects of FOXO Genotypes on Longevity: A Biodemographic Analysis
Yi Zeng et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2010)
Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity
Bjoern Schwer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
被撤回的出版物: Human SIRT6 Promotes DNA End Resection Through CtIP Deacetylation (Publication with Expression of Concern. See vol. 364, pg. 247, 2019) (Publication with Expression of Concern. See vol. 361, pg. 1322, 2018) (Retracted article. See vol. 364, pg. 247, 2019)
Abderrahmane Kaidi et al.
SCIENCE (2010)
SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair
Ronald A. McCord et al.
AGING-US (2009)
SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span
Tiara L. A. Kawahara et al.
CELL (2009)
Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6
Eriko Michishita et al.
CELL CYCLE (2009)
The sirtuin SIRT6 deacetylates H3 K56Ac in vivo to promote genomic stability
Bo Yang et al.
CELL CYCLE (2009)
FXR Acetylation Is Normally Dynamically Regulated by p300 and SIRT1 but Constitutively Elevated in Metabolic Disease States
Jongsook Kim Kemper et al.
CELL METABOLISM (2009)
FSH and FOXO1 Regulate Genes in the Sterol/Steroid and Lipid Biosynthetic Pathways in Granulosa Cells
Zhilin Liu et al.
MOLECULAR ENDOCRINOLOGY (2009)
Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner
Frederic Van Gool et al.
NATURE MEDICINE (2009)
Association of FOXO3A variation with human longevity confirmed in German centenarians
Friederike Flachsbart et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Association of the FOXO3A Locus with Extreme Longevity in a Southern Italian Centenarian Study
Chiara Viviani Anselmi et al.
REJUVENATION RESEARCH (2009)
FoxO1 integrates insulin signaling to VLDL production
Adama Kamagate et al.
CELL CYCLE (2008)
Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis
Sudha B. Biddinger et al.
CELL METABOLISM (2008)
SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin
Eriko Michishita et al.
NATURE (2008)
Hepatic insulin resistance directly promotes formation of cholesterol gallstones
Sudha B. Biddinger et al.
NATURE MEDICINE (2008)
FOXO3A genotype is strongly associated with human longevity
Bradley J. Wilicox et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
FoxO3 coordinately activates protein degradation by the Autophagic/Lysosomal and proteasomal pathways in atrophying muscle cells
Jinghui Zhao et al.
CELL METABOLISM (2007)
SIRT1 deacetylates and positively regulates the nuclear receptor LXR
Xiaoling Li et al.
MOLECULAR CELL (2007)
FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis
Ji-Hye Paik et al.
CELL (2007)
Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor foxo1 in liver
Michihiro Matsumoto et al.
CELL METABOLISM (2007)
FoxO1 regulates multiple metabolic pathways in the liver - Effects on gluconeogenic, glycolytic, and lipogenic gene expression
WW Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6
R Mostoslavsky et al.
CELL (2006)
Role of cholesterol and lipid organization in disease
FR Maxfield et al.
NATURE (2005)
Mouse Sir2 homolog SIRT6 is a nuclear ADP-ribosyltransferase
G Liszt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin
A Vaquero et al.
MOLECULAR CELL (2004)
Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes
JD Horton et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Coactivator-dependent acetylation stabilizes members of the SREBP family of transcription factors
V Giandomenico et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver
JD Horton et al.
JOURNAL OF CLINICAL INVESTIGATION (2002)
Share Paper
