Journal
JOURNAL OF LIPID RESEARCH
Volume 50, Issue -, Pages S311-S316Publisher
ELSEVIER
DOI: 10.1194/jlr.R800049-JLR200
Keywords
phospholipids; sphingolipids; plasmalogens; unfolded protein response
Categories
Funding
- National Institutes of Health [GM-45737]
- Cancer Center [CA21765]
- American Lebanese Syrian Associated Charities
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This review presents an overview of mammalian phospholipid synthesis and the cellular locations of the biochemical activities that produce membrane lipid molecular species. The generalized endoplasmic reticulum compartment is a central site for membrane lipid biogenesis, and examples of the emerging relationships between alterations in lipid composition, regulation of membrane lipid biogenesis, and cellular secretory function are discussed.-Fagone, P., and S. Jackowski. Membrane phospholipid synthesis and endoplasmic reticulum function. J. Lipid Res. 2009. S311-S316.
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