Journal
JOURNAL OF LIPID RESEARCH
Volume 50, Issue -, Pages S364-S369Publisher
ELSEVIER
DOI: 10.1194/jlr.R800092-JLR200
Keywords
inflammation; lymphocytes; cytokines
Categories
Funding
- Assistance Publique-Hopitaux de Paris
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There is now solid evidence that T cell adaptive immunity is involved in atherogenesis. While initial studies have focused on the pathogenic arm of the immune response, more recent work clearly suggests an important role for several subsets of regulatory T cells in the protection against lesion development. Here, we review the current knowledge on the role of both pathogenic and regulatory adaptive T cell immunity in atherosclerosis, generated mainly from the study of mouse models of the disease.-Mallat, Z., S. Taleb, H. Ait-Oufella, and A. Tedgui. The role of adaptive T cell immunity in atherosclerosis. J. Lipid Res. 2009. S364-S369.
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