Journal
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
Volume 55, Issue 6, Pages 201-205Publisher
WILEY
DOI: 10.1002/jlcr.2926
Keywords
isotopically labeled synthesis; carbon-14; deuterium; benzoxaborole; antimalarial agent; Plasmodium falciparum
Funding
- Medicines for Malaria Venture (MMV)
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Two new isotopically labeled compounds, (carboxy-13C-3,3-2H2)-7-(2-carboxyethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaborole (2) and (3-14C)-7-(2-carboxyethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaborole (3), were designed and synthesized to support the preclinical development studies of a potential new antimalarial agent, 7-(2-carboxyethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaborole (1). Copyright (c) 2012 John Wiley & Sons, Ltd.
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