Journal
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
Volume 55, Issue 1, Pages 5-9Publisher
WILEY-BLACKWELL
DOI: 10.1002/jlcr.1943
Keywords
63Zn; positron emitter; zinc purification; molecular imaging; radiopharmaceuticals; radiochemistry; PET
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This study presents the production and purification of the positron emitting radionuclide 63Zn. A natural copper target was irradiated with 13.5 MeV protons, and 63Zn was purified by cation exchange chromatography using 0.05 N HCl-85% acetone as eluent. The production yield reached 1.41 +/- 0.19 GBq/mu A center dot h at the end of bombardment and 169 +/- 30 MBq/mu A center dot h after purification, with more than 99.9% of radionuclidic purity with copper content around 0.04 mu g/g. Copyright (C) 2011 John Wiley & Sons, Ltd.
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