Journal
JOURNAL OF KOREAN MEDICAL SCIENCE
Volume 29, Issue 4, Pages 527-535Publisher
KOREAN ACAD MEDICAL SCIENCES
DOI: 10.3346/jkms.2014.29.4.527
Keywords
Aged, Eighty and over; Myocardial Infarction; Percutaneous Coronary Intervention
Categories
Ask authors/readers for more resources
We compared clinical characteristics, management, and clinical outcomes of nonagenarian acute myocardial infarction (AMI) patients (n= 270, 92.3 +/- 2.3 yr old) with octogenarian AMI patients (n= 2,145, 83.5 +/- 2.7 yr old) enrolled in Korean AMI Registry (KAMIR). Nonagenarians were less likely to have hypertension, diabetes and less likely to be prescribed with beta-blockers, statins, and glycoprotein IIb/IIIa inhibitors compared with octogenarians. Although percutaneous coronary intervention (PCI) was preferred in octogenarians than nonagenarians, the success rate of PCI between the two groups was comparable. In-hospital mortality, the composite of in-hospital adverse outcomes and one year mortality were higher in nonagenarians than in octogenarians. However, the composite of the one year major adverse cardiac events (MACEs) was comparable between the two groups without differences in MI or re-PCI rate. PCI improved 1-yr mortality (adjusted hazard ratio [HR], 0.50; 95% confidence interval [CI], 0.36-0.69, P < 0.001) and MACEs (adjusted HR, 0.47; 95% CI, 0.37-0.61, P < 0.001) without significant complications both in nonagenarians and octogenarians. In conclusion, nonagenarians had similar 1-yr MACEs rates despite of higher in-hospital and 1-yr mortality compared with octogenarian AMI patients. PCI in nonagenarian AMI patients was associated to better 1-yr clinical outcomes.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available