Journal
JOURNAL OF INTERNAL MEDICINE
Volume 266, Issue 2, Pages 141-153Publisher
WILEY
DOI: 10.1111/j.1365-2796.2009.02085.x
Keywords
cytokines; immunotherapy; lymphopenia; T cell
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Funding
- NCI
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Interleukin-7 (IL-7) is required for the development and survival of T cells and plays a critical role in modulating T-cell homeostasis. This review will address current understanding of IL-7 biology, review recent clinical experiences and discuss potential future clinical applications of IL-7, or IL-7 blockade, in the setting of disease.
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