4.7 Article

NK cells in HIV-1 infection: evidence for their role in the control of HIV-1 infection

Journal

JOURNAL OF INTERNAL MEDICINE
Volume 265, Issue 1, Pages 29-42

Publisher

WILEY
DOI: 10.1111/j.1365-2796.2008.02045.x

Keywords

HIV; innate immunity; Natural killer cells; viral immunity

Funding

  1. NIAID NIH HHS [R01 AI067031, R01 AI067031-04] Funding Source: Medline

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Increasing evidence supports the notion that the innate immune response, and in particular, natural killer cells play a central role in determining the quality of the host immune response to infection. In this review we highlight recent evidence that suggests that NK cells influence the clinical fate of HIV-infected individuals.

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