A variable neighborhood descent heuristic for the problem of makespan minimisation on unrelated parallel machines with setup times

The NP-hard problem of scheduling jobs on unrelated parallel machines, in the presence of machine-dependent and sequence-dependent setup times, with the objective of minimizing the makespan, is considered. A variable neighborhood descent search algorithm, hybridized with mathematical programming elements, is presented and its performance is evaluated on a large set of benchmark problem instances. The extensive computational experiments show that the proposed algorithm outperforms previously proposed methods in terms of solution quality as well as computation time.