Journal
JOURNAL OF INFECTIOUS DISEASES
Volume 203, Issue 3, Pages 372-377Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/infdis/jiq050
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Funding
- Swiss National Science Foundation [320030_118424, PDFMP3_124952]
- UK National Institute for Health Research (NIHR) [07/42/02]
- Swiss National Science Foundation (SNF) [PDFMP3_124952, 320030_118424] Funding Source: Swiss National Science Foundation (SNF)
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Repeated Chlamydia trachomatis infections after treatment are common. One reason is reinfection from untreated partners in ongoing sexual partnerships. Mathematical models that are used to predict the impact of screening on reducing chlamydia prevalence often do not incorporate reinfection and might overestimate the expected impact. We describe a pair compartmental model that explicitly incorporates sexual partnership duration and reinfection. The pair model predicts a weaker impact of screening when compared directly with a model that does not accommodate partnerships. Effective management of sex partners to prevent reinfection might need to be strengthened in chlamydia control programs.
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