4.7 Article

Persistent Infection with West Nile Virus Years after Initial Infection

Journal

JOURNAL OF INFECTIOUS DISEASES
Volume 201, Issue 1, Pages 2-4

Publisher

OXFORD UNIV PRESS INC
DOI: 10.1086/648731

Keywords

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Funding

  1. National Institutes of Health (NIH) [NIH/NIAID/DAIT N01 AI 50027-03, NIH/NIAID K23 AI057341, N01-A125489]
  2. US Department of Defense, Army [W81XWH-04-2-0035]
  3. University of Texas Health Science Center at Houston Committee for the Protection of Human Subjects [HSC-SPH-03-039]
  4. NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES [R01AI091816, K23AI057341, N01AI050027] Funding Source: NIH RePORTER

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West Nile virus (WNV) RNA was demonstrated in 5 (20%) of 25 urine samples collected from convalescent patients 573-2452 days (1.6-6.7 years) after WNV infection. Four of the 5 amplicons sequenced showed >99% homology to the WNV NY99 strain. These findings show that individuals with chronic symptoms after WNV infection may have persistent renal infection over several years.

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