Journal
JOURNAL OF INFECTION AND CHEMOTHERAPY
Volume 20, Issue 11, Pages 735-737Publisher
ELSEVIER
DOI: 10.1016/j.jiac.2014.07.003
Keywords
Environmental water; ESBL; Multilocus sequence typing; Bangladesh
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Funding
- Grants-in-Aid for Scientific Research [25461524] Funding Source: KAKEN
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Pathogens encoding extended-spectrum beta-lactamase (ESBL) genes represent a threat for failure of empirical antibiotic therapy and are associated with high mortality, morbidity and expenses. We examined surface water in Dhaka, capital of Bangladesh and isolated ESBL-producing Escherichia coli, Klebsiella pneumoniae and Enterobacter cloacae, suggesting the potential role of water for the dissemination and transmission of resistant genes among microorganisms. E. coli found most prevalent among isolated Enterobacteriaceae from environmental water. Molecular and genetic analysis revealed CTX-M-type and SHV-type ESBL genes in isolates that may influence the spread of multidrug resistant pathogenic bacteria causing human and animal infections in Bangladesh. (C) 2014, Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
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