Journal
JOURNAL OF INFECTION
Volume 59, Issue 5, Pages 303-307Publisher
W B SAUNDERS CO LTD
DOI: 10.1016/j.jinf.2009.08.019
Keywords
Clostridium difficile; Texas; Mortality; Death certificate data
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Objectives: Increased incidence of Clostridium difficile infection and deaths from US hospitals has occurred from 1996 to 2005. Methods: We examined C. difficile-related mortality rates in Texas and compared results with national trends. Results: In Texas, there were 1004 C. difficile-related deaths from 1999 to 2005 (586 (58%) attributed as the underlying cause and 418 (42%) attributed as a contributing cause). In 1999, 50 deaths were attributed as the underlying or contributing cause (0.2 per 100,000 population) versus 274 deaths in 2005 (1.2 per 100,000 population); corresponding to a 6-fold increase. There were approximately 4.5 times more hospital in-patient C. difficile-related deaths in 2005 (0.94 per 100,000) versus 1999 (0.21 per 100,000), and approximately 7 times more deaths in nursing homes in 2005 (0.14 per 100,000) than in 1999 (0.02 per 100,000). Conclusion: C. difficile has become an important public health concern with a significant mortality burden on the Texas population. (c) 2009 The British Infection Society. Published by Elsevier Ltd. All rights reserved.
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