Journal
JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
Volume 42, Issue 3, Pages 423-436Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s10295-014-1539-8
Keywords
-
Categories
Funding
- DARPA living foundries
- Office of Naval Research Young Investigator Program Award
- DARPA Living Foundries Program
- Welch Foundation [F-1753]
Ask authors/readers for more resources
A plethora of successful metabolic engineering case studies have been published over the past several decades. Here, we highlight a collection of microbially produced chemicals using a historical framework, starting with titers ranging from industrial scale (more than 50 g/L), to medium-scale (5-50 g/L), and lab-scale (0-5 g/L). Although engineered Escherichia coli and Saccharomyces cerevisiae emerge as prominent hosts in the literature as a result of well-developed genetic engineering tools, several novel native-producing strains are gaining attention. This review catalogs the current progress of metabolic engineering towards production of compounds such as acids, alcohols, amino acids, natural organic compounds, and others.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available