Related references
Note: Only part of the references are listed.Bioinformatic evaluation of the secondary metabolism of antistaphylococcal environmental bacterial isolates
Morgan A. Wyatt et al.
CANADIAN JOURNAL OF MICROBIOLOGY (2013)
Engineering the acyltransferase substrate specificity of assembly line polyketide synthases
Briana J. Dunn et al.
JOURNAL OF THE ROYAL SOCIETY INTERFACE (2013)
A genomic approach to the cryptic secondary metabolome of the anaerobic world
Anne-Catrin Letzel et al.
NATURAL PRODUCT REPORTS (2013)
antiSMASH 2.0-a versatile platform for genome mining of secondary metabolite producers
Kai Blin et al.
NUCLEIC ACIDS RESEARCH (2013)
Alternative Sigma Factor Over-Expression Enables Heterologous Expression of a Type II Polyketide Biosynthetic Pathway in Escherichia coli
David Cole Stevens et al.
PLOS ONE (2013)
Classification of the Adenylation and Acyl-Transferase Activity of NRPS and PKS Systems Using Ensembles of Substrate Specific Hidden Markov Models
Barzan I. Khayatt et al.
PLOS ONE (2013)
Heterologous Expression and Manipulation of Three Tetracycline Biosynthetic Pathways
Peng Wang et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)
NRPSsp: non-ribosomal peptide synthase substrate predictor
Carlos Prieto et al.
BIOINFORMATICS (2012)
PKMiner: a database for exploring type II polyketide synthases
Jinki Kim et al.
BMC MICROBIOLOGY (2012)
Discovery and Characterization of a Group of Fungal Polycyclic Polyketide Prenyltransferases
Yit-Heng Chooi et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Explorations of catalytic domains in non-ribosomal peptide synthetase enzymology
Gene H. Hur et al.
NATURAL PRODUCT REPORTS (2012)
A fungal ketoreductase domain that displays substrate-dependent stereospecificity
Hui Zhou et al.
NATURE CHEMICAL BIOLOGY (2012)
The Natural Product Domain Seeker NaPDoS: A Phylogeny Based Bioinformatic Tool to Classify Secondary Metabolite Gene Diversity
Nadine Ziemert et al.
PLOS ONE (2012)
Functional Gene-Guided Discovery of Type II Polyketides from Culturable Actinomycetes Associated with Soft Coral Scleronephthya sp
Wei Sun et al.
PLOS ONE (2012)
Structural and Biochemical Studies of the Hedamycin Type II Polyketide Ketoreductase (HedKR): Molecular Basis of Stereo- and Regiospecificities
Pouya Javidpour et al.
BIOCHEMISTRY (2011)
Stereoselectivity of Isolated Dehydratase Domains of the Borrelidin Polyketide Synthase: Implications for cis Double Bond Formation
Olivia Vergnolle et al.
CHEMBIOCHEM (2011)
NRPSpredictor2-a web server for predicting NRPS adenylation domain specificity
Marc Roettig et al.
NUCLEIC ACIDS RESEARCH (2011)
antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences
Marnix H. Medema et al.
NUCLEIC ACIDS RESEARCH (2011)
Functional analysis of environmental DNA-derived type II polyketide synthases reveals structurally diverse secondary metabolites
Zhiyang Feng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Mutagenesis of a Modular Polyketide Synthase Enoylreductase Domain Reveals Insights into Catalysis and Stereospecificity
David H. Kwan et al.
ACS CHEMICAL BIOLOGY (2010)
Genome Mining Reveals trans-AT Polyketide Synthase Directed Antibiotic Biosynthesis in the Bacterial Phylum Bacteroidetes
Roberta Teta et al.
CHEMBIOCHEM (2010)
SMURF: Genomic mapping of fungal secondary metabolite clusters
Nora Khaldi et al.
FUNGAL GENETICS AND BIOLOGY (2010)
Mechanism and Stereospecificity of a Fully Saturating Polyketide Synthase Module: Nanchangmycin Synthase Module 2 and Its Dehydratase Domain
Xun Guo et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
Stereospecificity of the Dehydratase Domain of the Erythromycin Polyketide Synthase
Chiara R. Valenzano et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
The Pfam protein families database
Robert D. Finn et al.
NUCLEIC ACIDS RESEARCH (2010)
SBSPKS: structure based sequence analysis of polyketide synthases
Swadha Anand et al.
NUCLEIC ACIDS RESEARCH (2010)
The Biosynthetic Logic of Polyketide Diversity
Christian Hertweck
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)
Automated genome mining for natural products
Michael H. T. Li et al.
BMC BIOINFORMATICS (2009)
Genomic islands link secondary metabolism to functional adaptation in marine Actinobacteria
Kevin Penn et al.
ISME JOURNAL (2009)
CLUSEAN: A computer-based framework for the automated analysis of bacterial secondary metabolite biosynthetic gene clusters
T. Weber et al.
JOURNAL OF BIOTECHNOLOGY (2009)
Biochemical Analysis of the Biosynthetic Pathway of an Anticancer Tetracycline SF2575
Lauren B. Pickens et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
SMART 6: recent updates and new developments
Ivica Letunic et al.
NUCLEIC ACIDS RESEARCH (2009)
Emergent gene order in a model of modular polyketide synthases
Benjamin Callahan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Biosynthesis of the salinosporamide A polyketide synthase substrate chloroethylmalonyl-coenzyme A from S-adenosyl-L-methionine
Alessandra S. Eustaquio et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Towards Prediction of Metabolic Products of Polyketide Synthases: An In Silico Analysis
Gitanjali Yadav et al.
PLOS COMPUTATIONAL BIOLOGY (2009)
In silico analysis of methyltransferase domains involved in biosynthesis of secondary metabolites
Mohd Zeeshan Ansari et al.
BMC BIOINFORMATICS (2008)
Prediction and Manipulation of the Stereochemistry of Enoylreduction in Modular Polyketide Synthases
David H. Kwan et al.
CHEMISTRY & BIOLOGY (2008)
Orchestration of discoid polyketide cyclization in the resistornycin pathway
Kathrin Fritzsche et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Exploiting the mosaic structure of trans-acyltransferase polyketide synthases for natural product discovery and pathway dissection
Tuanh Nguyen et al.
NATURE BIOTECHNOLOGY (2008)
Phylogeny.fr: robust phylogenetic analysis for the non-specialist
A. Dereeper et al.
NUCLEIC ACIDS RESEARCH (2008)
ClustScan: an integrated program package for the semi-automatic annotation of modular biosynthetic gene clusters and in silico prediction of novel chemical structures
Antonio Starcevic et al.
NUCLEIC ACIDS RESEARCH (2008)
Evolution of polyketide synthases in bacteria
Christian P. Ridley et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
NORINE: a database of nonribosomal peptides
Segolene Caboche et al.
NUCLEIC ACIDS RESEARCH (2008)
Complete genome sequence of the myxobacterium Sorangium cellulosum
Susanne Schneiker et al.
NATURE BIOTECHNOLOGY (2007)
Comprehensive analysis of distinctive polyketide and nonribosomal peptide structural motifs encoded in microbial genomes
Yohsuke Minowa et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
Phylogenetic analysis of condensation domains in NRPS sheds light on their functional evolution
Christian Rausch et al.
BMC EVOLUTIONARY BIOLOGY (2007)
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338
Markiyan Oliynyk et al.
NATURE BIOTECHNOLOGY (2007)
Polyketide synthases and nonribosomal peptide synthetases: the emerging view from bacterial genomics
Stefano Donadio et al.
NATURAL PRODUCT REPORTS (2007)
Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase
WJ Zhang et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2006)
Polyketide double bond biosynthesis. Mechanistic analysis of the dehydratase-containing module 2 of the picromycin/methymycin polyketide synthase
JQ Wu et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
Evolutionary implications of bacterial polyketide synthases
H Jenke-Kodama et al.
MOLECULAR BIOLOGY AND EVOLUTION (2005)
What is a hidden Markov model?
SR Eddy
NATURE BIOTECHNOLOGY (2004)
The erythromycin biosynthetic gene cluster of Aeromicrobium erythreum
IA Brikun et al.
JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY (2004)
Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei
J Piel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Chirality of peptide bond-forming condensation domains in nonribosomal peptide synthetases:: The C5 domain of tyrocidine synthetase is a DCL catalyst
SL Clugston et al.
BIOCHEMISTRY (2003)
Conserved amino acid residues correlating with ketoreductase stereospecificity in modular polyketicle synthases
P Caffrey
CHEMBIOCHEM (2003)
Computational approach for prediction of domain organization and substrate specificity of modular polyketide synthases
G Yadav et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)
A model of structure and catalysis for ketoreductase domains in modular polyketide synthases
R Reid et al.
BIOCHEMISTRY (2003)
A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles
J Piel
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Molecular evolution of aromatic polyketides and comparative sequence analysis of polyketide ketosynthase and 16S ribosomal DNA genes from various streptomyces species
M Metsä-Ketelä et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2002)
The hidden steps of domain skipping: Macrolactone ring size determination in the pikromycin modular polyketide synthase
BJ Beck et al.
CHEMISTRY & BIOLOGY (2002)
The biosynthesis of the aromatic myxobacterial electron transport inhibitor stigmatellin is directed by a novel type of modular polyketide synthase
N Gaitatzis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Biosynthesis of the anti-parasitic agent megalomicin:: transformation of erythromycin to megalomicin in Saccharopolyspora erythraea
Y Volchegursky et al.
MOLECULAR MICROBIOLOGY (2000)
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei
M Suwa et al.
GENE (2000)
Predictive, structure-based model of amino acid recognition by nonribosomal peptide synthetase adenylation domains
GL Challis et al.
CHEMISTRY & BIOLOGY (2000)
Share Paper
