4.7 Article

Antibacterial activity of dithiothreitol reduced graphene oxide

Journal

JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
Volume 19, Issue 4, Pages 1280-1288

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.jiec.2012.12.029

Keywords

Graphene oxide; Reduced graphene oxide; Dithiothreitol; E. coli; UV-visible spectroscopy; Raman spectroscopy

Funding

  1. SMART-Research Professor Program of Konkuk University
  2. Konkuk University SMART-Full time Professorship
  3. Woo Jang-Choon project [PJ007849]
  4. next generation of Biogreen 21 from the Rural Development Administration, Republic of Korea [PJ008169022012, PJ009107]
  5. Rural Development Administration (RDA), Republic of Korea [PJ008169022012] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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A green and simple approach is described for the large scale synthesis of reduced graphene oxide (rGO). The transition of graphene oxide (GO) into graphene was confirmed using various analytical techniques. Raman spectroscopy data indicate the partial removal of oxygen-containing functional groups from the surface of GO and formation of graphene. X-ray diffraction (XRD) was used to investigate the crystallinity of graphene nanosheets. The antibacterial activity of GO and rGO was evaluated using cell viability, reactive oxygen species (ROS) production and DNA fragmentation assays. The results suggest that GO and rGO possessed an excellent antimicrobial activity against Escherichia coli. (c) 2012 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.

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