4.6 Review

Small RNAs Guide Hematopoietic Cell Differentiation and Function

Journal

JOURNAL OF IMMUNOLOGY
Volume 184, Issue 11, Pages 5939-5947

Publisher

AMER ASSOC IMMUNOLOGISTS
DOI: 10.4049/jimmunol.0902567

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Funding

  1. GlaxoSmithKline-Immune Disease Institute Alliance

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MicroRNAs (miRNAs) are key regulators of gene expression that help direct normal differentiation and malignant transformation of hematopoietic cells. This review summarizes our current knowledge of how miRNAs function in normal and malignant hematopoiesis and how miRNAs might be applied for disease treatment. The Journal of Immunology, 2010, 184: 5939-5947.

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