4.8 Article

Green Method for the Synthesis of Chromeno[2,3-c]pyrazol-4(1H)-ones through Ionic Liquid Promoted Directed Annulation of 5-(Aryloxy)-1H-pyrazole-4-carbaldehydes in Aqueous Media

Journal

ORGANIC LETTERS
Volume 17, Issue 4, Pages 932-935

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.5b00033

Keywords

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Funding

  1. NSFC [21162025, 21262035]
  2. Program for Outstanding Youth Science and Technology Innovation Talents Training in Xinjiang Uygur Autonomous Region [2014721004]
  3. Natural Science Foundation of Xinjiang University [BS110133]
  4. Key Laboratory of Oil & Gas Fine Chemicals, Ministry of Education & Xinjiang Uyghur Autonomous Region [XJDX0908-2013-1, XJDX0908-2013-2]

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The first classical heterocyclic ionic liquid (IL) promoted C-H bond oxidant cross-doupling,reaction for the intramolecular annulation of 5-(aryloxy)-1H-pyrazole-4-carbal- dehydes to chromeno[2,37c]pyrazol-4(1H)-ones has been disclosed The promoter 1,3-dibutyl-1H-benzo[d]fl 2 3]- triazol-34-ium bromide can be easily recycled reused with the same efficacies for at least five cycles in aqueous medium The strategy works smoothly and provides applicable protocol to construct a Wide range of products.

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