Journal
ORGANIC LETTERS
Volume 17, Issue 24, Pages 6198-6201Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.5b03192
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Funding
- National Natural Science Foundation of China [21572078, 21372095]
- Natural Science Foundation of Anhui [1308085MB25]
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A room temperature decarboxylative ortho-acylation of acetanilides with a-oxocarboxylic acids has been developed via a novel Eosin Y with Pd dual catalytic system. This dual catalytic reaction shows a broad substrate scope and good functional group tolerance, and an array of ortho-acylacetanilides can be afforded in high yields under mild conditions.
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