Journal
ORGANIC LETTERS
Volume 17, Issue 12, Pages 3134-3137Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.5b01456
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Funding
- Max-Planck-Gesellschaft
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A novel and operationally simple one-step C-H bond functionalization of quinoline N-oxides to 2-substituted quinolines was developed. This approach enables the regioselective functionalization under external oxidant- and metal-free conditions. The developed transformation represents the first application of the Petasis reaction in functionalization of heterocycles.
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