Journal
ORGANIC LETTERS
Volume 17, Issue 6, Pages 1389-1392Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.5b00159
Keywords
-
Categories
Funding
- National Natural Science Foundation of China
- National Basic Research Program of China (973 Program) [2014CB745100]
- Tianjin Municipal Science & Technology Commission [14JCZDJC33400]
Ask authors/readers for more resources
A chiral phosphoric acid catalyzed enantioselective decarboxylative alkylation of beta-keto acids with 3-hydroxy-3-indolyloxindoles is described in this context. This method tolerates a series of aromatic and aliphatic beta-keto acids as well as substituted 3-hydroxy-3-indolyloxindoles, affording the corresponding chiral 3-functionalized 3-indolyloxindoles in high yields (up to 98%) and enantioselectivities (up to 99% ee).
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available