Journal
ORGANIC LETTERS
Volume 17, Issue 3, Pages 680-683Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol503707m
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Funding
- MEXT, Japan
- ACT-C from JST, Japan
- Grants-in-Aid for Scientific Research [26620086, 22105002] Funding Source: KAKEN
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A new cross-coupling reaction has been developed for the introduction of an alkyne moiety to an anisole derivative through C-O bond activation using an NHC ligand. This method has been used for direct alkynylation of a broad range of anisole derivatives and provided rapid access to compounds with potential applications in biological and materials science.
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