Carbonylative Mizoroki-Heck Reaction of Alkyl Iodides with Arylalkenes Using a Pd/Photoirradiation System

A carbonylative Mizorold-Heck reaction using alkyl iodides was achieved with a Pd/photoirradiation sysfem using DBU as a base. In this reaction,, alkyl radicals were formed from alkyl iodides via single-electron transfer (SET) and then underwent a sequential addition to CO and alkenes to give beta-keto radicals. It is proposed that DBU would abstract a proton a to carbonyl to form radical anions, giving alpha,beta-unsaturated ketones via SET.