Journal
JOURNAL OF IMMUNOLOGICAL METHODS
Volume 396, Issue 1-2, Pages 8-14Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jim.2013.08.010
Keywords
Helicobacter pylori; Lateral flow immunoassay; Immunochromatography; Colloidal gold
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Helicobacter pylori infection is the most common human infection where approximately 50% of the world populations are infected. The diagnosis of such infection is mainly done by endoscopy where gastric biopsies are examined for the presence of H. pylori. Such invasive approach is costly, time consuming and generally requires more than one test to confirm the infection. Serology on the other hand is a non-invasive approach that can detect H. pylori exposure. The lateral flow immunoassays (LFIA) support the serological approach and have the advantage of being fast, economic and require no additional equipment or experience. In this review the principles, components of the LFIA, sensitivities and specificities of the commercially available H. pylori test strips were compared and discussed. (C) 2013 Elsevier B.V. All rights reserved.
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