Journal
ORGANIC LETTERS
Volume 17, Issue 12, Pages 3050-3053Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.5b01334
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Funding
- National Natural Science Foundation of P.R. China [21372202, 21402175]
- New Century Excellent Talents in University [NCET-12-1086]
- Zhejiang Natural Science Fund [R14B020005]
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A novel copper/I-2-mediated oxidative cross-coupling/cyclization of 2-(pyridin-2-yl)acetate derivatives and simple olefins is developed, which provides a straightforward and efficient access to structural diversely indolizines. A series of 1,3-di- and 1,2,3-trisubstituted indolizines are easily synthesized in modest to excellent yields.
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