Journal
ORGANIC LETTERS
Volume 17, Issue 3, Pages 736-739Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.5b00015
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Funding
- EPFL
- F. Hoffmann-La Roche, Ltd.
- ERC [334840]
- European Research Council (ERC) [334840] Funding Source: European Research Council (ERC)
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A one-pot three-component protocol for the preparation of arylsulfonyl alkynes through the reaction of ethynyl-benziodoxolone (EBX) reagents, DABSO (DABCO.SO2), and either organomagnesium reagents or aryl iodides with a palladium catalyst is reported. A broad range of aryl and heteroarylalkynyl sulfones were obtained in 46-85% overall yield.
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