Journal
ORGANIC LETTERS
Volume 17, Issue 17, Pages 4300-4303Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.5b02114
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- Max-Planck-Gesellschaft
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A synthesis of multisubstituted furans from readily available acetophenones and electron-deficient alkynes via direct C(sp(3))-H bond functionalization under radical reaction conditions is described. The developed transformation is catalyzed by copper(I) salts using di-tert-butyl peroxide as an external oxidant. This method offers an efficient access to biologically important scaffolds from simple compounds.
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