Journal
JOURNAL OF HYPERTENSION
Volume 32, Issue 6, Pages 1222-1228Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/HJH.0000000000000175
Keywords
blood pressure; health behaviors; hypertension; longitudinal study; optimism; risk factors; vitality; well being; Whitehall II cohort
Categories
Funding
- Robert Wood Johnson Foundation
- Medical Research Council [K013351]
- National Institute on Aging [AG13196]
- National Heart Lung and Blood Institute [HL36310]
- British Heart Foundation
- Michael Smith Foreign Study Supplement (Canadian Institutes of Health Research)
- Medical Research Council
- professorial fellowship from the Economic and Social Research Council
- Economic and Social Research Council [ES/J023299/1] Funding Source: researchfish
- Medical Research Council [MR/K013351/1] Funding Source: researchfish
- ESRC [ES/J023299/1] Funding Source: UKRI
- MRC [MR/K013351/1] Funding Source: UKRI
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Background:Previous studies have shown that psychological well being is associated with reduced risk of cardiovascular disease. However, whether well being might be specifically associated with reduced risk of hypertension has not been rigorously investigated in prospective studies.Objective:This study examined the prospective association between two measures of psychological well being and incident hypertension.Methods:Participants were 6384 healthy British civil servants aged 39-63 from the Whitehall II cohort. Psychological well being (emotional vitality and optimism) and cardiovascular risk factors (demographic characteristics, health status, health behaviors, psychological ill being) were assessed during the 1991-1994 baseline. Incident hypertension was defined by clinical measures of SBP or DBP at least 140/90mmHg, self-reported physician-diagnosed hypertension, or treatment for hypertension. Follow-up assessments of hypertension took place approximately every 3 years through 2002-2004. Cox proportional hazards regression models estimated hazard ratios.Results:There were 2304 cases of incident hypertension during the follow-up period. High versus low emotional vitality was associated with a significantly reduced risk of hypertension in an age-adjusted model (hazard ratio=0.89; 95% confidence interval 0.80-0.98). This association was maintained after controlling for demographic characteristics and health status, but was slightly attenuated after adjusting for health behaviors and ill being. Optimism was not significantly associated with hypertension.Conclusion:High emotional vitality was associated with reduced hypertension risk; favorable health behaviors explained only part of the relationship. Associations did not differ by age, were similar for men and women, and were maintained after accounting for ill being.
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