Journal
ORGANIC LETTERS
Volume 17, Issue 4, Pages 1018-1021Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.5b00131
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Funding
- NSFC [21072063, 21372085]
- GNSF [10351064101000000]
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The first Cu(II)-catalyzed highly enantioselective intramolecular cyclization of N-alkenylureas was developed for the concise assembly of chiral vicinal diamino bicyclic heterocycles. Facile removal of carbonyl group of the carbamido moiety allowed for ready access to enantioenriched cyclic vicinal diamines.
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