Journal
ORGANIC LETTERS
Volume 17, Issue 23, Pages 5886-5889Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.5b03068
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Funding
- National Science Council, Taiwan [MOST103-2113-M-002-002-MY3]
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One-pot sequential reactions of aryldiazonium salts with amidines followed by the treatment of I-2/KI under basic conditions provide 2,5-disubstituted tetrazoles in moderate to excellent yields. This one-pot synthesis has several advantages such as mild reaction conditions, short reaction time, convenient workup, and high yields, making this methodology practical.
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