Journal
ORGANIC LETTERS
Volume 17, Issue 10, Pages 2416-2419Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.5b00928
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Funding
- Ministry of Education, Culture, Sports, Science and Technology, Japan
- Workshop on Chirality at Chiba University (WCCU)
- Grants-in-Aid for Scientific Research [26105706] Funding Source: KAKEN
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An (S,S)-diphenyldiamine-derived bis(imidazolidine)pyridine (PyBidine)-NiCl2 complex catalyzed the asymmetric addition of methanol and peroxides to isatin-derived N-Boc-imines to form chiral quaternary N,O-acetals at the C3 position of the resulting oxiindoles in up to 99% yield with 94% ee.
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