Journal
ORGANIC LETTERS
Volume 17, Issue 14, Pages 3466-3469Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.5b01510
Keywords
-
Categories
Funding
- BBSRC
- ARC [SAE20131200603]
- European Union [H2020-MSCA-IF-2014-658405, FP7-PEOPLE-2012-ITN-316882]
- Royal Society
- Biotechnology and Biological Sciences Research Council [1112421] Funding Source: researchfish
Ask authors/readers for more resources
The synthesis of arylCF(2)CF(2)SiMe(3) and their reactivity in cross-coupling reactions with aryl iodides and aryl bromides to afford a range of 1,1,2,2-tetrafluoro-1,2-aryl-ethanes is reported. The use of pyridine as an alternative to phenanthroline, and the ability to carry out the reaction at 60 degrees C or room temperature are the key features of this Cu-Ag mediated cross-coupling methodology. The chemistry is compatible with (hetero)aryl halides, offering a platform to develop products of interest in material and medicinal chemistry.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available