Journal
ORGANIC LETTERS
Volume 17, Issue 6, Pages 1381-1384Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.5b00077
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Funding
- NNSFC [21272087, 21472058, 21202053, 21232003]
- National Basic Research Program of China (973 program) [2011CB808603]
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A general and efficient Pd/sulfoxide-phosphine complex-catalyzed direct asymmetric N-allylic alkylation of indoles has been developed to allow for the preparation of various N-allylated indoles in generally good yields with excellent enantioselectivities. This catalytic system could also be extended to other N-containing heterocycles with good results.
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