4.8 Article

A One-Pot Synthesis of Dibenzofurans from 6-Diazo-2-cyclohexenones

Journal

ORGANIC LETTERS
Volume 17, Issue 23, Pages 5744-5747

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.5b02783

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Funding

  1. NSFC [21302077, 21472072, 21172100, 21272105, 21290183]
  2. Program for Changjiang Scholars and Innovative Research Team in University [PCSIRT: IRT1138]
  3. FRFCU [lzujbky-2013-ct02]
  4. 111 Program of MOE

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A novel and efficient protocol for the rapid construction of dibenzofuran motifs from 6-diazo-2-cyclohexenone and ortho-haloiodobenzene has been developed. The process involves one-pot Pd-catalyzed cross-coupling/aromatization and Cu-catalyzed Ullmann coupling.

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