4.8 Article

Gallium(III)-Promoted Halocyclizations of 1,6-Diynes

Journal

ORGANIC LETTERS
Volume 17, Issue 9, Pages 2126-2129

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.5b00716

Keywords

-

Funding

  1. NIGMS CMLD initiative [P50 GM067041]
  2. Boston University Undergraduate Research Opportunities Program (UROP)
  3. Direct For Mathematical & Physical Scien
  4. Division Of Chemistry [1156666] Funding Source: National Science Foundation

Ask authors/readers for more resources

Cyclization of 1,6-diynes promoted by stoichiometric Ga(III) halides produces vinyl halides in good to excellent yields. Under acidic conditions, initially formed iodocyclization products undergo in situ Friedel-Crafts cyclizations, giving access to iodoindenopyridines. Application of the vinyl halides in cross-coupling reactions has been explored, and mechanistic aspects of the cyclization are discussed.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.8
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available