Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 13, Issue 2, Pages 409-423Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4ob01951b
Keywords
-
Categories
Funding
- Agence Nationale de la Recherche [ANK-12-BSV1-0026-02]
- Universite Paris Descartes
- Centre National de la Recherche Scientifique
- Ministere de l'Education Nationale, de l'Enseignement Superieur et de la Recherche
Ask authors/readers for more resources
The synthesis of 4-amino-3-cyano-N-arylpyrazoles A based on a Thorpe-Ziegler cyclization as the key step has been achieved using microwave activation. Via a new diversity-oriented synthetic pathway, these highly functionalized building blocks allowed the access to various heteroaromatic scaffolds such as pyrazolo-pyridines B, pyrazolo-pyrimidines C and pyrazolo-oxadiazoles D. Interestingly, these platforms contain three to four reactive sites that could be used for post-functionalization in order to further increase the molecular diversity.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available