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A review: microRNA detection methods

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 13, Issue 8, Pages 2226-2238

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4ob02104e

Keywords

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Funding

  1. National Basic Research Program of China (973 Program) [2012CB720600, 2012CB720603]
  2. National Science Foundation of China [91213302, 21272181, 81373256]
  3. National Grand Program on Key Infectious Dis-ease [2012ZX10003002-014]

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MicroRNA (miRNA) detection is of considerable significance in both disease diagnosis and in the study of miRNA function. The importance of miRNA itself is due to the complicated regulatory functions it plays in various life processes and its close relationship with some diseases. Traditional methods for miRNA detection do not meet the current demands, so various novel methods have been developed with a special focus on sensitivity and specificity. Herein, we summarize and discuss the newly developed miRNA detection methods.

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