Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 13, Issue 43, Pages 10631-10640Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5ob01586c
Keywords
-
Categories
Funding
- CSIR, New Delhi
- CSIR
- Indus MAGIC (CSC) [0123]
- DST New Delhi [SR/S1/OC-42/2014]
Ask authors/readers for more resources
Titanium superoxide efficiently catalysed the oxidative esterification of aldehydes with alkylarenes or alcohols, under truly heterogeneous conditions, to afford the corresponding benzyl and alkyl esters in excellent yields. Mechanistic studies have established that this one pot direct oxidative esterification process proceeds through a radical pathway, proven by a FTIR spectral study of a titanium superoxide-aldehyde complex as well as spin trapping experiments with TEMPO. The intramolecular version of this protocol has been successfully demonstrated in the concise synthesis of 3-butylphthalide, an anti-convulsant drug.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available