Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 13, Issue 19, Pages 5344-5348Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5ob00209e
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Funding
- State Key Program of National Natural Science of China [21236002]
- National Basic Research Program of China [2010CB126100]
- National High Technology Research and Development Program of China [2011AA10A207]
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A fluorescent probe for sensitive detection of hydrazine based on an ESIPT mechanism and a substitution-cyclization-elimination cascade was developed. After the addition of hydrazine, an approximately 50-fold enhancement in fluorescence intensity at 465 nm was observed and the subsequent decrease at 375 nm was observed in 10 min with a detection limit of 0.147 mu M. We also detected hydrazine in HeLa cells successfully.
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