Journal
JOURNAL OF HUMAN HYPERTENSION
Volume 28, Issue 3, Pages 157-164Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/jhh.2013.81
Keywords
arterial stiffness; wave reflection; blood pressure; strength training; exercise
Categories
Funding
- American Heart Association (BGIA) [0765139Y]
- National Heart, Lung and Blood Institute [P50 HL105188]
- National Center for Advancing Translational Sciences through UCLA CTSI [UL1TR000124]
- American Heart Association [10SDG305006]
Ask authors/readers for more resources
Central blood pressure is a predictor of the risk of cardiovascular disease (CVD), and the effects of resistance training (RT) on central blood pressure are largely unknown. This study explored the effects of high-intensity RT on central blood pressure, indices of arterial stiffness and wave reflection and inflammatory/atherogenic markers in overweight or obese, sedentary young men. Thirty-six participants were randomized to RT (12 weeks of training, 3/wk, n = 28) or control groups (C, 12 weeks of no training, n = 8) and assessed for changes in central and brachial blood pressures, augmentation index (AIx), carotid-femoral pulse wave velocity (cfPWV), carotid intima-media thickness (cIMT), body composition, lipids and inflammatory/atherogenic markers. High-intensity RT resulted in decreased central and brachial systolic/diastolic blood pressures (all P <= 0.03), despite not altering AIx (P = 0.34) or cfPWV (P = 0.43). The vascular endothelial growth factor increased (P 0.03) after RT, without any change in cIMT, C-reactive protein, oxidized LDL (oxLDL) or other inflammatory markers (all P >= 0.1). Changes in the central systolic blood pressure (cSBP) were positively correlated with changes in oxLDL (r = 0.42, P = 0.03) and soluble E-selectin (r = 0.41, P = 0.04). In overweight/obese young men, high-intensity RT decreases cSBP, independently of weight loss and changes in arterial stiffness. The cardioprotective effects of RT may be related to effects on central blood pressure.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available