3.9 Article

Cumulative live birth rate after three ovarian stimulation IVF cycles for poor ovarian responders according to the bologna criteria

Publisher

SPRINGER
DOI: 10.1007/s11596-013-1134-7

Keywords

ovarian stimulation; in vitro fertilization; Bologna criteria; poor responders; cumulative live birth

Funding

  1. Comprehensive Strategic Sciences Cooperation Projects of Guangdong Province and Chinese Academy [2010B090301026]
  2. Guangzhou Science and Technology Program Key Projects [11C22120737]
  3. National Natural Science Foundation of China [81170574]
  4. Southern Medical University

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This study explored the cumulative live birth rate after three ovarian stimulation in vitro fertilization (IVF) cycles for poor ovarian responders according to the Bologna criteria. In this retrospective cohort study, 479 poor ovarian responders according to the Bologna criteria in the first ovarian stimulation IVF cycle between July 2006 and January 2012 in our IVF centre were included. The cumulative live birth rate was calculated by optimistic and pessimistic methods. The cumulative live birth rate after three ovarian stimulation IVF cycles for poor ovarian responders according to the Bologna criteria was 12.7%-20.5%. The three-cycle cumulative live birth rate was 18.5%-24.5%, 13.2%-27.4% and 8.6%-14.9% for poor responders aged a parts per thousand currency sign35 years, 36-39 years and a parts per thousand yen40 years, respectively. In conclusion, poor responders according to the Bologna criteria can receive an acceptable cumulative live birth rate after three ovarian stimulation IVF cycles, especially poor responders aged < 40 years.

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