Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 13, Issue 12, Pages 3556-3560Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5ob00018a
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Funding
- UGC & CSIR, New Delhi
- DST, Government of India [SR/S1/OC-13/2011]
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Copper-mediated synthesis of pyrazolo[1,5-a] pyridine-3-carboxylates through oxidative linkage of C-C and N-N bonds under mild reaction conditions is described. This protocol is applicable to a variety of pyridyl esters as well as various benzonitriles including nicotinonitrile, isonicotinonitrile and thiophene-2-carbonitrile. Better yields were observed with electron withdrawing substituted benzonitriles.
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