Journal
JOURNAL OF HETEROCYCLIC CHEMISTRY
Volume 55, Issue 10, Pages 2315-2324Publisher
WILEY
DOI: 10.1002/jhet.3291
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A variety of 3-substituted-6,8-dimethylchromones have been synthesized and characterized. The chemical reactivity of 3-substituted-6,8-dimethylchromones was studied towards some nucleophiles, namely, S-benzyldithiocarbazate, o-phenylenediamine, and cyanoacetamide, and a diversity of products were efficiently synthesized. Reactions of 3-substituted-6,8-dimethylchromones (except 3-formyl-6,8-dimethylchromone), with nucleophilic reagents, usually proceed through nucleophilic attack at C-2 position followed by different types of heterocyclization depending on the functional group present at C-3 position. Structures of the newly synthesized products have been established based on elemental analysis and spectral data.
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