Journal
JOURNAL OF HETEROCYCLIC CHEMISTRY
Volume 48, Issue 6, Pages 1302-1307Publisher
WILEY
DOI: 10.1002/jhet.762
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The synthesis of chiral (2R) 2,5-diaryl-2,3-dihydropyrano[2,3-b]quinolin-4-ones, was achieved, at ambient temperature, by the reaction of 3-acetyl-4-aryl-carbostyril and an aldehyde, in the presence of bismuth triflate-L(-)-proline complex, formed in situ. The products were obtained in 62-78% yield with high enantioselectivity (72-96% ee).
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