4.4 Article

One-Pot and Three-Component Synthesis of Spiro[chromeno[2,3-d] pyrimidine-5,3′-indoline]-diones and Spiro[chromeno[2,3-c] pyrazole-4,3′-indoline]-diones

Journal

JOURNAL OF HETEROCYCLIC CHEMISTRY
Volume 47, Issue 4, Pages 967-972

Publisher

WILEY-BLACKWELL
DOI: 10.1002/jhet.399

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A novel, clean, one-pot and three-component synthesis of new spiroichromeno[2,3-d]pyrimidine-5,3'-indoline]-2',6(7H)-diones and spiro[chromeno[2,3-c]pyrazole-4,3'-indoline]-2',5(6H)-diones via cyclo-condensation reaction of isatins, 1,3-cyclohexadiones, and 2-methylpyrimidine-4,6-diol or 3-methyl-1-phenyl-1H-pyrazol-5-ol, in aqueous media is reported.

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