4.4 Article

One-Pot Synthesis of 2,3-Dihydro-2-thioxoquinazolin-4(1H)-ones from Nitro-Compounds with the Aid of Tin(II) Chloride

Journal

JOURNAL OF HETEROCYCLIC CHEMISTRY
Volume 47, Issue 4, Pages 939-943

Publisher

WILEY-BLACKWELL
DOI: 10.1002/jhet.392

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Funding

  1. Key Laboratory of Organic Synthesis of Jiangsu Province

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A facile synthetic method using SnCl(2)center dot 2H(2)O system to promote the novel reductive cyclization of 2-nitrobenzamides and isothiocyanates is described. Sequentially, a series of 2,3-dihydro-2-thioxoquinazolin-4(1H)-ones were synthesized in good yields.

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