Journal
JOURNAL OF HETEROCYCLIC CHEMISTRY
Volume 47, Issue 4, Pages 949-953Publisher
WILEY
DOI: 10.1002/jhet.394
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Funding
- Islamic Azad University (TAU), Saveh Branch
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In a one-pot procedure, the 3-phenacylideneoxindoles 1a-d were reacted with hydrazine and then in situ with lead(IV) acetate and new diastereoisomers of spiro[cyclopropane-1,3'-[3H]indol]-2'(1'H)ones were prepared. Compounds 1a-d underwent a highly diastereoselective cyclopropanation leading to diastereoisomers 2a-d. These new compounds containing both 2-oxindole and cyclopropane moieties may be valuable in medicinal chemistry.
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